GITC

Application Guanidinium thiocyanate or guanidinium isothiocyanate (GITC) is a chemical compound used as a general protein denaturant, being a chaotropic agent, although it is most commonly used as a nucleic acid protector in the extraction of DNA and RNA from cells. GITC may also be recognized as guanidine thiocyanate. This is because guanidinium is the conjugate acid of guanidine and is called the guanidinium cation, [CH6N3]+.

Synonyms Acide thiocyanique – guanidine (1:1) [French]; Guanidine isothiocyanate; Guanidine thiocyanate; Guanidinium rhodanide; Guanidinium thiocyanate; Guandine thiocyanate; GUANIDINE MONOTHIOCYANATE; Isothiocyanic acid; Thiocyanate; Thiocyanic acid

CAS Number 593-84-0 | EINECS 209-812-1 | Beilstein Registry Number 3563461 | MDL Number MFCD00013027 |Molecular Formula C2H6N4S | Molecular Weight 118.161

SMILES C(#N)S.C(=N)(N)N

StdInChI InChI=1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

StdInChIKey ZJYYHGLJYGJLLN-UHFFFAOYSA-N

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  • PRODUCT DETAILS

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    Properties of GITC

    AppearanceWhite crystalline powder
    Melting Point116~121°C

    Description of GITC

    Assay99% min
    Ash0.1% max
    Water0.3% max
    Water-Insoluble Matter0.1% max
    NH4CL0.1% max
    A(208nm)35% in water M.P0.4 max
    A(300nm)35% in water M.P0.1 max
    pH(11.8% in water)5-7
    Shelf Life1 year
    StorageUnder room temperature and away from light
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    SymbolHazard and Precautionary CorrosionHazard and Precautionary SkullGHS05,GHS07
    Signal WordDanger
    Hazard StatementsH302+H312+H332-H314-H412
    Precautionary StatementsP260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
    Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
    Supplemental Hazard StatementsContact with acids liberates very toxic gas
    RIDADRUN 1759 8 / PGIII
    WGK Germany2
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    None Available

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    Guanidine thiocyanate CAS 593-84-0 at Watson International Ltdhttps://www.watson-int.com/guanidine-thiocyanate-cas-593-84-0/
    Guanidine thiocyanate CAS 593-84-0 at Caming Pharmaceutical Ltdhttps://www.caming.com/guanidine-thiocyanate-cas-593-84-0/
    Guanidine thiocyanate CAS 593-84-0 at Watson Noke Scientific Ltdhttps://www.watsonnoke.com/guanidine-thiocyanate-cas-593-84-0/
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